Human Insight Machine Intelligence

Category: Project

  • Alignment-Free, Neural-Network-Based RNA-Seq Computational Analysis.

    Alignment-Free, Neural-Network-Based RNA-Seq Computational Analysis.

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    by

    gbwiersum
    in

    Using an Autoencoder Neural-Network to characterize cell types in Bulk RNA-Seq data. Background The cornerstone of traditional distance calculation (Hosangadi, 2012), (Thompson et al. 2005) is the multiple sequence alignment (msa). In an MSA, sequences are matched nucleotide-to-nucleotide and a score is given to each nucleotide pair that either matches, is mismatched, or presents a…